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In overweight women, up to 55% of total body weight can be composed of water, with fluctuations driven by variables such as dietary salt intake, stress levels, and hormonal shifts. Remarkably, during periods of acute illness, dehydration, or extreme stress, the body can deplete its “structural hydration” reserves—water stored within muscle membranes—at an accelerated rate. This can lead to weight changes of up to 15 pounds within just 24 hours. These dramatic shifts are further influenced by fluid redistribution processes, which can temporarily disguise true changes in fat mass, creating a physiological illusion of rapid weight gain or loss. Such variability underscores the intricate balance of the body’s hydration mechanisms and their significant impact on short-term weight dynamics.